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Repo-Man Controls a Protein Phosphatase 1-dependent Threshold for DNA Damage Checkpoint Activation
BACKGROUND: In response to DNA damage, cells activate checkpoints to halt cell cycle progression and prevent genomic instability. Checkpoint activation induced by DNA double strand breaks (DSB) is dependent on the ATM kinase, a master regulator of the DDR that is activated through autophosphorylatio...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860455/ https://ncbi.nlm.nih.gov/pubmed/20188555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.020 |
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