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Genome assembly quality: Assessment and improvement using the neutral indel model
We describe a statistical and comparative-genomic approach for quantifying error rates of genome sequence assemblies. The method exploits not substitutions but the pattern of insertions and deletions (indels) in genome-scale alignments for closely related species. Using two- or three-way alignments,...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860169/ https://ncbi.nlm.nih.gov/pubmed/20305016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.096966.109 |
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