Llwytho...

Genome assembly quality: Assessment and improvement using the neutral indel model

We describe a statistical and comparative-genomic approach for quantifying error rates of genome sequence assemblies. The method exploits not substitutions but the pattern of insertions and deletions (indels) in genome-scale alignments for closely related species. Using two- or three-way alignments,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Meader, Stephen, Hillier, LaDeana W., Locke, Devin, Ponting, Chris P., Lunter, Gerton
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860169/
https://ncbi.nlm.nih.gov/pubmed/20305016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.096966.109
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