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A synthetic circuit for selectively arresting daughter cells to create aging populations

The ability to engineer genetic programs governing cell fate will permit new safeguards for engineered organisms and will further the biological understanding of differentiation and aging. Here, we have designed, built and implemented a genetic device in the budding yeast Saccharomyces cerevisiae th...

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Autori principali: Afonso, Bruno, Silver, Pamela A., Ajo-Franklin, Caroline M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860115/
https://ncbi.nlm.nih.gov/pubmed/20150416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq075
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