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Interaction between Human Mismatch Repair Recognition Proteins and Checkpoint sensor Rad9-Rad1-Hus1

In eukaryotic cells, the cell cycle checkpoint proteins Rad9, Rad1, and Hus1 form the 9-1-1 complex which is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp. hMSH2/hMSH6 (hMutSα) and hMSH2/hMSH3 (hMutSβ) are the mismatch recognition factors of the mismatch repair...

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Autores principales: Bai, Haibo, Madabushi, Amrita, Guan, Xin, Lu, A-Lien
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860068/
https://ncbi.nlm.nih.gov/pubmed/20188637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.01.011
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