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N-glycosylation enhances presentation of an MHC class I restricted epitope from tyrosinase

We recently demonstrated that the mechanism of processing of an HLA-A*0201-restricted peptide epitope, Tyr(369)(D), derived from the membrane protein tyrosinase, involves retrotranslocation of glycosylated molecules from the endoplasmic reticulum to the cytosol; removal of an N-linked carbohydrate f...

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Autors principals: Ostankovitch, Marina, Altrich-VanLith, Michelle, Robila, Valentina, Engelhard, Victor H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859980/
https://ncbi.nlm.nih.gov/pubmed/19342661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802902
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