Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by MHC class I in vitro and in woodchucks

In this report, the possibility of pharmacologically altering the hepatitis B virus (HBV) epitopes presented by major histocompatibility complex (MHC) class I on infected cells is demonstrated. The HBV middle envelope glycoprotein MHBs maturation appears to require calnexin mediated folding. This in...

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Detalhes bibliográficos
Main Authors: Norton, Pamela A., Menne, Stephan, Sinnathamby, Gomathinayagam, Betesh, Lucy, Cote, Paul J., Philip, Ramila, Mehta, Anand S., Tennant, Bud C., Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947625/
https://ncbi.nlm.nih.gov/pubmed/20658465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23806
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