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Medial forebrain stimulation enhances intracranial nociception and attenuates morphine analgesia suggesting the existence of an endogenous opioid antagonist

The purpose of this experiment was to test in the rat the hypotheses that activation of the brain reward system would attenuate the effects of intracranial nociceptive stimulation and would potentiate the antinociceptive effects of morphine. In this experiment pain (nociception) was generated by ele...

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Detalhes bibliográficos
Main Authors: Kornetsky, Conan, Knapp, Clifford M., Tozier, Lisa, Pak, Arlene
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859829/
https://ncbi.nlm.nih.gov/pubmed/20149816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.01.015
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