RSK2 Signaling in Medial Habenula Contributes to Acute Morphine Analgesia

It has been established that mu opioid receptors activate the ERK1/2 signaling cascade both in vitro and in vivo. The Ser/Thr kinase RSK2 is a direct downstream effector of ERK1/2 and has a role in cellular signaling, cell survival growth, and differentiation; however, its role in biological process...

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Autors principals: Darcq, Emmanuel, Befort, Katia, Koebel, Pascale, Pannetier, Solange, Mahoney, Megan K, Gaveriaux-Ruff, Claire, Hanauer, André, Kieffer, Brigitte L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306890/
https://ncbi.nlm.nih.gov/pubmed/22218090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.316
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