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RSK2 signaling in brain habenula contributes to place aversion learning

RSK2 is a Ser/Thr kinase acting in the Ras/MAPK pathway. Rsk2 gene deficiency leads to the Coffin-Lowry Syndrome, notably characterized by cognitive deficits. We found that mrsk2 knockout mice are unable to associate an aversive stimulus with context in a lithium-induced conditioned place aversion t...

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Detalhes bibliográficos
Main Authors: Darcq, Emmanuel, Koebel, Pascale, Del Boca, Carolina, Pannetier, Solange, Kirstetter, Anne-Sophie, Garnier, Jean-Marie, Hanauer, André, Befort, Katia, Kieffer, Brigitte L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256568/
https://ncbi.nlm.nih.gov/pubmed/21852432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2221011
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