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Medial forebrain stimulation enhances intracranial nociception and attenuates morphine analgesia suggesting the existence of an endogenous opioid antagonist

The purpose of this experiment was to test in the rat the hypotheses that activation of the brain reward system would attenuate the effects of intracranial nociceptive stimulation and would potentiate the antinociceptive effects of morphine. In this experiment pain (nociception) was generated by ele...

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Hlavní autoři: Kornetsky, Conan, Knapp, Clifford M., Tozier, Lisa, Pak, Arlene
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859829/
https://ncbi.nlm.nih.gov/pubmed/20149816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.01.015
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