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Insufficient deactivation of the protein tyrosine kinase Lck amplifies T-cell responsiveness in acute coronary syndrome

RATIONALE: In the vulnerable atherosclerotic plaque, T cells may destabilize the tissue structure through direct cell-injurious effector functions. T cells transmit environmental signals, such as recognition of antigen, into cellular responses through regulated phosphorylation of cytoplasmic protein...

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Main Authors: Pryshchep, Sergey, Goronzy, Jörg J., Parashar, Susmita, Weyand, Cornelia M.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859828/
https://ncbi.nlm.nih.gov/pubmed/20035083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.206052
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