A cancer derived mutation in the Retinoblastoma gene with a distinct defect for LXCXE dependent interactions

BACKGROUND: The interaction between viral oncoproteins such as Simian virus 40 TAg, adenovirus E1A, and human papilloma virus E7, and the retinoblastoma protein (pRB) occurs through a well characterized peptide sequence, LXCXE, on the viral protein and a well conserved groove in the pocket domain of...

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Detalhes bibliográficos
Main Authors: Henley, Shauna A, Francis, Sarah M, Demone, Jordan, Ainsworth, Peter, Dick, Frederick A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Primary research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859746/
https://ncbi.nlm.nih.gov/pubmed/20298605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-8
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