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A cancer derived mutation in the Retinoblastoma gene with a distinct defect for LXCXE dependent interactions
BACKGROUND: The interaction between viral oncoproteins such as Simian virus 40 TAg, adenovirus E1A, and human papilloma virus E7, and the retinoblastoma protein (pRB) occurs through a well characterized peptide sequence, LXCXE, on the viral protein and a well conserved groove in the pocket domain of...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859746/ https://ncbi.nlm.nih.gov/pubmed/20298605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-8 |
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