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The balance between pre- and post-transfer editing in tRNA synthetases
The fidelity of tRNA aminoacylation is dependent in part on amino acid editing mechanisms. A hydrolytic activity that clears mischarged tRNAs typically resides in an active site on the tRNA synthetase that is distinct from its synthetic aminoacylation active site. A second pre-transfer editing pathw...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859721/ https://ncbi.nlm.nih.gov/pubmed/19941860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.071 |
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