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CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase

Mistranslation is toxic to bacterial and mammalian cells and can lead to neurodegeneration in the mouse. Mistranslation is caused by the attachment of the wrong amino acid to a specific tRNA. Many aminoacyl-tRNA synthetases have an editing activity that deacylates the mischarged amino acid before ca...

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Detalhes bibliográficos
Main Authors: Boniecki, Michal T., Vu, Michael T., Betha, Aswini K., Martinis, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614743/
https://ncbi.nlm.nih.gov/pubmed/19020078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809336105
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