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In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity

Aminoacyl-tRNA synthetases are essential enzymes that help to ensure the fidelity of protein translation by accurately aminoacylating (or “charging”) specific tRNA substrates with cognate amino acids. Many synthetases have an additional catalytic activity to confer amino acid editing or proofreading...

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Main Authors: Splan, Kathryn E., Musier-Forsyth, Karin, Boniecki, Michal T., Martinis, Susan A.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270698/
https://ncbi.nlm.nih.gov/pubmed/18241793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.10.009
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