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In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity
Aminoacyl-tRNA synthetases are essential enzymes that help to ensure the fidelity of protein translation by accurately aminoacylating (or “charging”) specific tRNA substrates with cognate amino acids. Many synthetases have an additional catalytic activity to confer amino acid editing or proofreading...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2270698/ https://ncbi.nlm.nih.gov/pubmed/18241793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.10.009 |
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