Eos mediates Foxp3-dependent gene silencing in regulatory T cells

Regulatory T cells (Treg) are critical to the maintenance of immunological self-tolerance and immune homeostasis by suppressing aberrant or excessive immune responses. Treg specifically express the transcription factor Foxp3, which mediates the coordinate activation of genes such as CTLA-4 and GITR...

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Bibliographic Details
Main Authors: Pan, Fan, Yu, Hong, Dang, Eric V., Barbi, Joseph, Pan, Xiaoyu, Grosso, Joseph F., Jinasena, Dinili, Sharma, Sudarshana M., McCadden, Erin M., Getnet, Derese, Drake, Charles G., Liu, Jun O., Ostrowski, Michael C., Pardoll, Drew M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859703/
https://ncbi.nlm.nih.gov/pubmed/19696312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1176077
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