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Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target

Naïve T cells activated by antigen-presenting cells (APC) can be differentiated into at least four major types of T-helper (T(H)) cells: T(H)1, T(H)2, T(H)17 and inducible regulatory T cells (iTreg) based on their unique cytokine production profiles and characteristic functions.(1) T(H)1 produce int...

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Detalhes bibliográficos
Main Authors: Pan, Fan, Barbi, Joseph, Pardoll, Drew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382896/
https://ncbi.nlm.nih.gov/pubmed/22754770
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