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Hypermethylated cap 4 maximizes Trypanosoma brucei translation

Through trans-splicing of a 39-nt Spliced Leader (SL) onto each protein-coding transcript, mature kinetoplastid mRNA acquire a hypermethylated 5′-cap structure, but its function has been unclear. Gene deletions for three Trypanosoma brucei cap 2′-O-ribose methyltransferases, TbMTr1, TbMTr2, and TbMT...

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Bibliografische gegevens
Hoofdauteurs: Zamudio, Jesse R., Mittra, Bidyottam, Campbell, David A., Sturm, Nancy R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859698/
https://ncbi.nlm.nih.gov/pubmed/19504740
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