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Complete Cap 4 Formation Is Not Required for Viability in Trypanosoma brucei

In kinetoplastids spliced leader (SL) RNA is trans-spliced onto the 5′ ends of all nuclear mRNAs, providing a universal exon with a unique cap. Mature SL contains an m(7)G cap, ribose 2′-O methylations on the first four nucleotides, and base methylations on nucleotides 1 and 4 (AACU). This structure...

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Detalhes bibliográficos
Main Authors: Zamudio, Jesse R., Mittra, Bidyottam, Zeiner, Gusti M., Feder, Marcin, Bujnicki, Janusz M., Sturm, Nancy R., Campbell, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489268/
https://ncbi.nlm.nih.gov/pubmed/16757738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00080-06
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