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Trypanosoma brucei Spliced Leader RNA Maturation by the Cap 1 2′-O-Ribose Methyltransferase and SLA1 H/ACA snoRNA Pseudouridine Synthase Complex

Kinetoplastid flagellates attach a 39-nucleotide spliced leader (SL) upstream of protein-coding regions in polycistronic RNA precursors through trans splicing. SL modifications include cap 2′-O-ribose methylation of the first four nucleotides and pseudouridine (ψ) formation at uracil 28. In Trypanos...

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Detalhes bibliográficos
Main Authors: Zamudio, Jesse R., Mittra, Bidyottam, Chattopadhyay, Arnab, Wohlschlegel, James A., Sturm, Nancy R., Campbell, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643836/
https://ncbi.nlm.nih.gov/pubmed/19103757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01496-08
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