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Proenzyme Structure and Activation of Astacin Metallopeptidase
Proteolysis is regulated by inactive (latent) zymogens, with a prosegment preventing access of substrates to the active-site cleft of the enzyme. How latency is maintained often depends on the catalytic mechanism of the protease. For example, in several families of the metzincin metallopeptidases, a...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859558/ https://ncbi.nlm.nih.gov/pubmed/20202938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097436 |
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