Structure of the catalytic domain of the Tannerella forsythia matrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor

Karilysin is the only metallopeptidase identified as a virulence factor in the odontopathogen Tannerella forsythia owing to its deleterious effect on the host immune response during bacterial infection. The very close structural and sequence-based similarity of its catalytic domain (Kly18) to matrix...

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Bibliografske podrobnosti
Main Authors: Guevara, Tibisay, Ksiazek, Miroslaw, Skottrup, Peter Durand, Cerdà-Costa, Núria, Trillo-Muyo, Sergio, de Diego, Iñaki, Riise, Erik, Potempa, Jan, Gomis-Rüth, F. Xavier
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2013
Teme:
Structural Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660881/
https://ncbi.nlm.nih.gov/pubmed/23695557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113007392
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