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Structure-Function Studies of the Staphylococcal Methicillin Resistance Antirepressor MecR2

Methicillin resistance in Staphylococcus aureus is elicited by the MecI-MecR1-MecA axis encoded by the mec locus. Recently, MecR2 was also identified as a regulator of mec through binding of the methicillin repressor, MecI. Here we show that plasmid-encoded full-length MecR2 restores resistance in a...

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Detalhes bibliográficos
Main Authors: Arêde, Pedro, Botelho, Tiago, Guevara, Tibisay, Usón, Isabel, Oliveira, Duarte C., Gomis-Rüth, F. Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774396/
https://ncbi.nlm.nih.gov/pubmed/23733184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448134
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