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Proteolysis of mecA Repressor Is Essential for Expression of Methicillin Resistance by Staphylococcus aureus

Recently, we have demonstrated that the cognate regulatory locus of the mecA gene in methicillin-resistant Staphylococcus aureus (MRSA) is in fact a three-component system containing the novel mecR2 gene coding for an antirepressor. MecR2 interacts with the repressor MecI, disturbing its binding to...

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Autori principali: Arêde, Pedro, Oliveira, Duarte C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623340/
https://ncbi.nlm.nih.gov/pubmed/23403422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02510-12
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