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Structural Basis of Dimerization-dependent Ubiquitination by the SCF(Fbx4) Ubiquitin Ligase

The F-box proteins are the substrate recognition subunits of the SCF (Skp1-Cul1-Rbx1-F- box protein) ubiquitin ligase complexes that control the stability of numerous regulators in eukaryotic cells. Here we show that dimerization of the F-box protein Fbx4 is essential for SCF(Fbx4) (the superscript...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Yunfeng, Hao, Bing
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859552/
https://ncbi.nlm.nih.gov/pubmed/20181953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111518
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