RyR1-mediated Ca(2+) Leak and Ca(2+) Entry Determine Resting Intracellular Ca(2+) in Skeletal Myotubes

The control of resting free Ca(2+) in skeletal muscle is thought to be a balance of channels, pumps, and exchangers in both the sarcolemma and sarcoplasmic reticulum. We explored these mechanisms using pharmacologic and molecular perturbations of genetically engineered (dyspedic) muscle cells that c...

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Hlavní autoři: Eltit, José M., Yang, Tianzhong, Li, Hongli, Molinski, Tadeusz F., Pessah, Isaac N., Allen, Paul D., Lopez, José R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859541/
https://ncbi.nlm.nih.gov/pubmed/20207743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107300
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