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The Importin β Binding Domain Modulates the Avidity of Importin β for the Nuclear Pore Complex
Importin β mediates active passage of cellular substrates through the nuclear pore complex (NPC). Adaptors such as importin α and snurportin associate with importin β via an importin β binding (IBB) domain. The intrinsic structural flexibility of importin β allows its concerted interactions with IBB...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859540/ https://ncbi.nlm.nih.gov/pubmed/20197273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095760 |
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