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Sequential Rearrangement of Interhelical Networks Upon Rhodopsin Activation in Membranes: the Meta II(a) Conformational Substate

Photon absorption by rhodopsin is proposed to lead to an activation pathway that is described by the extended reaction scheme: Meta I ⇋ Meta II(a) ⇋ Meta II(b) ⇋ Meta II(b)H(+); where Meta II(b)H(+) is thought to be the conformational substate that activates the G protein transducin. Here we test th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zaitseva, Ekaterina, Brown, Michael F., Vogel, Reiner
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859452/
https://ncbi.nlm.nih.gov/pubmed/20230054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910317a
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