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Sequential Rearrangement of Interhelical Networks Upon Rhodopsin Activation in Membranes: the Meta II(a) Conformational Substate
Photon absorption by rhodopsin is proposed to lead to an activation pathway that is described by the extended reaction scheme: Meta I ⇋ Meta II(a) ⇋ Meta II(b) ⇋ Meta II(b)H(+); where Meta II(b)H(+) is thought to be the conformational substate that activates the G protein transducin. Here we test th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859452/ https://ncbi.nlm.nih.gov/pubmed/20230054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910317a |
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