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A proteomic study of cMyc improvement of CHO culture

BACKGROUND: The biopharmaceutical industry requires cell lines to have an optimal proliferation rate and a high integral viable cell number resulting in a maximum volumetric recombinant protein product titre. Nutrient feeding has been shown to boost cell number and productivity in fed-batch culture,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuystermans, Darrin, Dunn, Michael J, Al-Rubeai, Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859402/
https://ncbi.nlm.nih.gov/pubmed/20307306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-25
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