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Stable transfection of CHO cells with the c-myc gene results in increased proliferation rates, reduces serum dependency, and induces anchorage independence
Induction of the transcription factor Myc promotes cell proliferation and transformation by activating growth-promoting genes and/or by transcriptionally repressing the expression of growth arrest genes. However, a number of studies have shown that c-Myc is a potent inducer of apoptosis in the absen...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449757/ https://ncbi.nlm.nih.gov/pubmed/19002957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1024203518501 |
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