Tumor-targeted delivery of biologically active TRAIL protein

The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a potent inducer of tumor cell apoptosis, but concerns of considerable liver toxicity limit its uses in human cancer therapy. Here, we show that i.v. injected Escherichia coli DH5α (E. coli DH5α) specifically replicates in...

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Detalhes bibliográficos
Main Authors: Zhang, H-Y, Man, J-H, Liang, B, Zhou, T, Wang, C-H, Li, T, Li, H-Y, Li, W-H, Jin, B-F, Zhang, P-J, Zhao, J, Pan, X, He, K, Gong, W-L, Zhang, X-M, Li, A-L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859322/
https://ncbi.nlm.nih.gov/pubmed/20075981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.76
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