Structure, Mechanism and Regulation of Pyruvate Carboxylase

Pyruvate carboxylase (PC) is a biotin-containing enzyme that catalyses the HCO(3)(−)- and MgATP-dependent carboxylation of pyruvate to form oxaloacetate. This is a very important anaplerotic reaction, replenishing oxaloacetate withdrawn from the Krebs cycle for various pivotal biochemical pathways....

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Main Authors: Jitrapakdee, Sarawut, Maurice, Martin St., Rayment, Ivan, Cleland, W. Wallace, Wallace, John C., Attwood, Paul V.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859305/
https://ncbi.nlm.nih.gov/pubmed/18613815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080709
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