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A general method for quantifying sequence effects on nucleobase oxidation in DNA

Oxidative damage to DNA has long been associated with aging and disease, with guanine serving as the primary target for oxidation owing to its low ionization potential. Emerging evidence points to a critical role for sequence context as a determinant of the guanine ionization potential and the assoc...

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Bibliografiske detaljer
Main Authors: Margolin, Yelena, Dedon, Peter C.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859239/
https://ncbi.nlm.nih.gov/pubmed/20013187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-029-8_19
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