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Leucine-Rich Repeat Kinase 2 Gene-Associated Disease: Redefining Genotype-Phenotype Correlation

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) has emerged as the most prevalent genetic cause of Parkinson's disease (PD) among Caucasians. Patients carrying an LRRK2 mutation display significant variability of clinical and pathologic phenotypes across and within affected families. METHODS:...

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Detalhes bibliográficos
Main Authors: Wider, Christian, Dickson, Dennis W., Wszolek, Zbigniew K.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859237/
https://ncbi.nlm.nih.gov/pubmed/20197701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000289232
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