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Multiple Molecular Interactions Determine the Clustering of Caspr2 and Kv1 Channels in Myelinated Axons

Clustering of Kv1 channels at the juxtaparanodal region (JXP) in myelinated axons depends on their association with the Caspr2/TAG-1 adhesion complex. The interaction between these channels and Caspr2 was suggested to depend on PDZ (PSD-95/Discs large/zona occludens-1) scaffolding proteins. Here, we...

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Hlavní autoři: Horresh, Ido, Poliak, Sebastian, Grant, Seth, Bredt, David, Rasband, Matthew N., Peles, Elior
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859216/
https://ncbi.nlm.nih.gov/pubmed/19109503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3398-08.2008
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