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Organization of Myelinated Axons by Caspr and Caspr2 Requires the Cytoskeletal Adapter Protein 4.1B

Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction (PNJ), whereas Caspr2 serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region (JXP). Both...

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Detalhes bibliográficos
Main Authors: Horresh, Ido, Bar, Vered, Kissil, Joseph L., Peles, Elior
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836844/
https://ncbi.nlm.nih.gov/pubmed/20164332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5225-09.2010
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