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Organization of Myelinated Axons by Caspr and Caspr2 Requires the Cytoskeletal Adapter Protein 4.1B

Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction (PNJ), whereas Caspr2 serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region (JXP). Both...

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Detalles Bibliográficos
Autores principales: Horresh, Ido, Bar, Vered, Kissil, Joseph L., Peles, Elior
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836844/
https://ncbi.nlm.nih.gov/pubmed/20164332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5225-09.2010
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