Juxtaparanodal clustering of Shaker-like K(+) channels in myelinated axons depends on Caspr2 and TAG-1

In myelinated axons, K(+) channels are concealed under the myelin sheath in the juxtaparanodal region, where they are associated with Caspr2, a member of the neurexin superfamily. Deletion of Caspr2 in mice by gene targeting revealed that it is required to maintain K(+) channels at this location. Fu...

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Detalhes bibliográficos
Main Authors: Poliak, Sebastian, Salomon, Daniela, Elhanany, Hadas, Sabanay, Helena, Kiernan, Brent, Pevny, Larysa, Stewart, Colin L., Xu, Xiaorong, Chiu, Shing-Yan, Shrager, Peter, Furley, Andrew J.W., Peles, Elior
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172860/
https://ncbi.nlm.nih.gov/pubmed/12963709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305018
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