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Juxtaparanodal clustering of Shaker-like K(+) channels in myelinated axons depends on Caspr2 and TAG-1
In myelinated axons, K(+) channels are concealed under the myelin sheath in the juxtaparanodal region, where they are associated with Caspr2, a member of the neurexin superfamily. Deletion of Caspr2 in mice by gene targeting revealed that it is required to maintain K(+) channels at this location. Fu...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172860/ https://ncbi.nlm.nih.gov/pubmed/12963709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305018 |
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