Characterization of the Murine SIRT3 Mitochondrial Localization Sequence and Comparison of Mitochondrial Enrichment and Deacetylase Activity of Long and Short SIRT3 Isoforms

SIRT3 is identified as the major mitochondrial deacetylase. Two distinct isoforms of the murine SIRT3 have been identified with the short isoform having no recognizable mitochondrial localization sequence (MLS) and the long isoform having a putative MLS. A recent study questions the mitochondrial de...

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Main Authors: Bao, Jianjun, Lu, Zhongping, Joseph, Joshua J., Carabenciov, Darin, Dimond, Christopher C., Pang, Liyan, Samsel, Leigh, McCoy, J. Philip, Leclerc, Jaime, Nguyen, PhuongMai, Gius, David, Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858784/
https://ncbi.nlm.nih.gov/pubmed/20235147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22531
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