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Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction
Epithelial-mesenchymal transition (EMT) is a phenotypic change in which epithelial cells detach from their neighbors and become motile. Whereas soluble signals such as growth factors and cytokines are responsible for stimulating EMT, here we show that gradients of mechanical stress define the spatia...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858775/ https://ncbi.nlm.nih.gov/pubmed/20336666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22545 |
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