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A Threonine-based Targeting Signal in the Human CD1d Cytoplasmic Tail Controls its Functional Expression

CD1d molecules are MHC class I-like molecules that present lipids to a unique subpopulation of T cells called natural killer T (NKT) cells. The cytoplasmic tail of human CD1d possesses a tyrosine-based endosomal targeting motif (YXXZ). As such, these molecules traffic through the endocytic pathway,...

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Detalhes bibliográficos
Main Authors: Liu, Jianyun, Shaji, Daniel, Cho, Sungyoo, Du, Wenjun, Gervay-Hague, Jacquelyn, Brutkiewicz, Randy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858764/
https://ncbi.nlm.nih.gov/pubmed/20368272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901448
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