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Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging

BACKGROUND: Age is a major risk for cardiovascular diseases. Although mitochondrial reactive oxygen species (ROS) have been proposed as one of the causes of aging, their role in cardiac aging remains unclear. We have previously shown that overexpression of catalase targeted to mitochondria (mCAT) pr...

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Detalhes bibliográficos
Main Authors: Dai, Dao-Fu, Santana, Luis F., Vermulst, Marc, Tomazela, Daniela M., Emond, M.J., MacCoss, Michael J., Gollahon, Katherine, Martin, George M., Loeb, Lawrence A., Ladiges, Warren C., Rabinovitch, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858759/
https://ncbi.nlm.nih.gov/pubmed/19451351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.822403
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