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Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine-Related Metabolic Pathways

Riboswitches are regulatory elements modulating gene expression in response to specific metabolite binding. It has been recently reported that riboswitch agonists may exhibit antimicrobial properties by binding to the riboswitch domain. Guanine riboswitches are involved in the regulation of transpor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mulhbacher, Jérôme, Brouillette, Eric, Allard, Marianne, Fortier, Louis-Charles, Malouin, François, Lafontaine, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858708/
https://ncbi.nlm.nih.gov/pubmed/20421948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000865
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