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Proteolysis of Human Thrombin Generates Novel Host Defense Peptides
The coagulation system is characterized by the sequential and highly localized activation of a series of serine proteases, culminating in the conversion of fibrinogen into fibrin, and formation of a fibrin clot. Here we show that C-terminal peptides of thrombin, a key enzyme in the coagulation casca...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858699/ https://ncbi.nlm.nih.gov/pubmed/20421939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000857 |
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