Oligomerized Pool ENgineering (OPEN): An “Open-Source” Protocol for Making Customized Zinc Finger Arrays

Engineered zinc finger nucleases (ZFNs) form the basis of a broadly applicable method for targeted, efficient modification of eukaryotic genomes. In recent work, we described OPEN (Oligomerized Pool ENgineering), an “open-source,” combinatorial selection-based method for engineering zinc finger arra...

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Autors principals: Maeder, Morgan L., Thibodeau-Beganny, Stacey, Sander, Jeffry D., Voytas, Daniel F., Joung, J. Keith
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858690/
https://ncbi.nlm.nih.gov/pubmed/19798082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.98
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