Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow

IL-13 and eotaxin play important, inter-related roles in asthma models. In the lungs, CysLT, produced by the 5-LO-LTC4S pathway, mediate some local responses to IL-13 and eotaxin; in bone marrow, CysLT enhance IL-5-dependent eosinophil differentiation. We examined the effects of IL-13 and eotaxin on...

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Detalhes bibliográficos
Main Authors: Queto, Tulio, Gaspar-Elsas, Maria I., Masid-de-Brito, Daniela, Vasconcelos, Zilton F. M., Ferraris, Fausto K., Penido, Carmen, Cunha, Fernando Q., Kanaoka, Yoshihide, Lam, Bing K., Xavier-Elsas, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858675/
https://ncbi.nlm.nih.gov/pubmed/20219953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1108709
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